(A)SCI Journal
1.
CJ Lin, CY Lin, YT Lin, CY Huang, KC Wei, JC
Chen, GJL Chen, HL Liu*, ¡§Microbubble-Facilitated Ultrasound
Pulsation Promotes Direct £\-Synuclein Gene Delivery,¡¨ Biochemical and Biophysical Research
Communications, Vol. 517, No. 1, pp. 77-83, 2019 (*³q°T§@ªÌ; IF = 2.466, 38/375 in¡§Biophysics¡¨).
2.
CH Wu, HL Liu, CT Ho, PH Hsu, CH
Fan, CK Yeh, ST Kang, WS Chen, FN Wang, HH Peng, ¡§Monitoring of acoustic
cavitation in microbubble-presented focused ultrasound exposure using
gradient-echo magnetic resonance imaging,¡¨ Journal of Magnetic Resonance Imaging, Accepted, 2019 (IF=3.732,
26/125 in ¡§Radiology¡¨).
3.
CY Lin, CH Tsai, LY Feng, WY Chai, CJ Lin, CY
Huang, KC Wei, CK Yeh, CM Chen, HL Liu, ¡§Focused
Ultrasound-Induced Blood Brain-Barrier Opening Enhanced Vascular
Permeability for GDNF Delivery in Huntington's Disease Mouse Model,¡¨ Brain Stimulation, Accepted,
2019 (*³q°T§@ªÌ; IF=6.919,
22/252 in ¡§Neuroscience¡¨).
4.
KT Chen, KC Wei and HL Liu*, ¡§Theranostic
Strategy of Focused Ultrasound Induced Blood-Brain Barrier Opening for CNS
Disease Treatment,¡¨ Frontiers in
Pharmacology, Vol. 10, pp. 1-16, 2019 (*³q°T§@ªÌ; IF: 3.845, 59/261
in Pharmacology and Pharmacy).
5.
IC Lee, HJ Wu, HL Liu*, ¡§Dual-frequency ultrasound
induces neural stem/progenitor cell differentiation and growth factor
utilization by enhancing stable cavitation,¡¨ ACS Chemical Neuroscience, Vol. 10, pp. 1-18, DOI:
10.1021/acschemneuro.8b00483, 2018 (*³q°T§@ªÌ; IF: 3.861, 83/261 in ¡§Neuroscience¡¨)
6.
HC Tsai, CH Tsai, WS Chen, C Inserra, KC Wei, HL Liu*,
"Safety evaluation of frequent application of microbubble-enhanced
focused ultrasound blood-brain-barrier opening," Scientific Reports, Vol. 8,
pp.1-13, 2018. (*³q°T§@ªÌ; IF=4.011, 15/64 in ¡§ Multidisciplinary Sciences¡¨)
7.
HL Liu*, CH Tsai, CK Jan, HY Chang, SM Huang, ML Li,
W Qiu, H Zheng, ¡§Design and Implementation of a Dual-Transmit/Receive-Mode
Therapeutic Ultrasound Phased Array System for Brain Therapy,¡¨ IEEE Transactions on Ultrasonics,
Ferroelectrics, and Frequency Control, Vol. 65 , No. 10, Opp. 1756 ¡V
1767, 2018 (IF = 2.989, 6/31 in ¡§Acoustics¡¨)
8.
SM Huang, HL Liu, DW Li, and ML Li, ¡§Ultrasonic Nakagami
Imaging of High-intensity Focused Ultrasound-Induced Thermal Lesions in
Porcine Livers: Ex Vivo Study,¡¨ Ultrasonic
Imaging, Accepted, 2018 (IF = 2.49,
9/31 in¡§Acoustics¡¨).
9.
PH Hsu, YT Lin, YH Chung, KJ Lin, LY Yang, TC Yen, and HL Liu*,
"Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3
Inhibitor Delivery for Amyloid-Beta Plaque Reduction," Scientific Reports, Vol. 8,
pp.1-12, 2018. (*³q°T§@ªÌ; IF=4.011, 15/64 in ¡§ Multidisciplinary Sciences¡¨).
10.
CH Tsai, KT Chen, YX Lin, YC Lin, WS Chen, C Inserra, and HL
Liu*, ¡§Acoustic Emission-Feedback Planar Ultrasound System for
Localized Blood-Brain Barrier Opening Monitoring, ¡§ Journal of Medical and Biological Engineering, Vol. 39, No.
3, pp. 277-286, 2018
(*³q°T§@ªÌ; SCI IF = 1.306, 66/76 in ¡§Engineering, Biomedical¡¨).
11.
WY Chai, PC Chu, CH Tsai, CY Lin, HW Yang, HY Lai, HL Liu*,
¡§Image-Guided Focused-Ultrasound CNS Molecular Delivery: An Implementation
via Dynamic Contrast-Enhanced Magnetic-Resonance Imaging,¡¨ Scientific Reports, 7;8(1):4151.
doi: 10.1038/s41598-018-22571-8, 2018 (*³q°T§@ªÌ; IF=4.011, 15/64 in
¡§ Multidisciplinary Sciences¡¨). link
12.
ZH Zhou, SC Wu, MY Lin, J Fang, HL Liu*, and PH Tsui*,
¡§Three-dimensional visualization of ultrasound backscatter statistics by
window-modulated compounding Nakagami imaging,¡¨ Ultrasonic Imaging, Vol. 40, No. 3, pp.171-189, 2018 (*³q°T§@ªÌ; IF = 2.49, 9/31 in¡§Acoustics¡¨). link
13.
Y Kung, C Lan, MY Hsiao, MK Sun, YH Hsu, APH Liao, WH Liao, HL
Liu, C Inserra, WS Chen, ¡§Focused shockwave induced blood-brain
barrier opening and transfection,¡¨
Scientific Reports, 2218, doi:10.1038/s41598-018-20672-y, 2018 (IF=4.011, 15/64 in ¡§ Multidisciplinary Sciences¡¨). link
14.
MT Tsai, JW Zhang, KC Wei, CK Yeh, HL Liu*, ¡§Assessment
of temporary cerebral effects induced by focused ultrasound with optical
coherence tomography angiography,¡¨ Biomedical
Optics Express, Vol. 9, No. 2, pp.507-517, 2018. (IF = 3.91, 15/96 in ¡§Optics¡¨) link
15.
C Cornua, M Guédraa, J-C Béraa, HL Liu, WS Chen, C
Inserraa, Ultrafast monitoring and control of subharmonic emissions of an
unseeded bubble cloud during pulsed sonication, Ultrasonics Sonochemistry, Vol.42, pp. 697¡V703, 2018. (IF=7.279, 1/31 in ¡§Acoustics¡¨). link
16.
FCM
Wu, WH Hsu, HL Liu, T Yonezawa,A Balcytis, S Juodkazis,and K
Hatanaka, ¡§Photoacoustic signal enhancements from gold nano-colloidal
suspensions excited by a pair of polarized time-delayed femtosecond
pulses,¡¨ Optics Express,
Vol. 25, pp. 19497-19507, 2017 (IF = 3.356, 19/96 in
¡§Optics¡¨).
17.
CH
Fan, CY Lin, HL Liu*, and CK Yeh*, ¡§Ultrasound Targeted CNS
Gene Delivery for Parkinson¡¦s Disease Treatment,¡¨ Journal of Controlled Release, Vol. 261, pp. 246-262, 2017 (*³q°T§@ªÌ;
IF = 7.877, 9/256 in ¡§Pharmacology & Pharmacy¡¨).
18.
Lee,
JC Yeh, CH Tsai, JT Yang, SL Lou, CJ Seak, CY Wang, KC Wei, HL Liu*,
¡§Improved thrombolytic effect with focused ultrasound and neuroprotective
agent against acute carotid artery thrombosis in rat,¡¨ Scientific Reports, 7(1):1638.
doi: 10.1038/s41598-017-01769-2., 2017. (*³q°T§@ªÌ;
IF=4.122, 16/64 in ¡§ Multidisciplinary Sciences¡¨).
19.
SK Wu,
PC Chu, WY Chai, ST Kang, CH Tsai, CH Fan, CK Yeh, HL Liu*,
¡§Characterization of Different Microbubbles in Assisting Focused
Ultrasound-Induced Blood-Brain Barrier Opening,¡¨ Scientific Reports, 7:46689. doi: 10.1038/srep46689., 2017.
(*³q°T§@ªÌ; IF=4.122, 16/64 in ¡§
Multidisciplinary Sciences¡¨)
20.
PY
Chen, CK Yeh, PH Hsu, CY Lin, CY Huang, KC Wei, HL Liu*,
¡§Drug-carrying Microbubbles as a Theranostic Tool in Convection-Enhanced
Delivery for Brain Tumor Therapy,¡¨ Oncotarget,
Vol. 8, No. 26, pp.42359-42371, 2017. (*³q°T§@ªÌ;
IF = 5.168, 44/217 in
"Oncology") link
21.
P
Rwei, CSA Gong, LJ Luo, MB Lin, JY Lai*, HL Liu*, ¡§In vitro
investigation of ultrasound-induced oxidative stress on human lens
epithelial cells,¡¨ Biochemical and
Biophysical Research Communications, Vol. 482, pp.954-960, 2017 (*³q°T§@ªÌ;
IF = 2.466, 38/375 in
¡§Biophysics¡¨). link
22.
HH Peng, CH Wu, ST Kang, JW
Zhang, HL Liu, WS Chen,
CH Wang, CK Yeh, ¡§Real-Time Monitoring of Inertial Cavitation Effects of Microbubbles
by Using MRI: In Vitro Experiments,¡¨ Magnetic Resonance in Medicine, Vol. 77, No. 1, pp.102-111, 2017 (IF=4.082, 19/126 in
¡§Radiology¡¨) link
23.
MT Tsai, JW Zhang,
YH Liu, CK Yeh, KC Wei, and HL Liu*, ¡§Acoustic-actuated
optical coherence angiography,¡¨ Optics
Letters, Vol. 41, pp. 5813-5816, 2016 (*³q°T§@ªÌ; IF = 3.589, 14/96 in "Optics") link
24.
PC Chu, Wen-Yen
Chai, CH Tsai, ST Kang, CK Yeh and HL Liu*, ¡§Focused
Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical
Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced
Magnetic-Resonance Imaging,¡¨ Scientific
Reports, 6:33264, doi: 10.1038/srep33264, 2016 (*³q°T§@ªÌ; IF=4.122, 16/64 in ¡§
Multidisciplinary Sciences¡¨). link
25.
FCP Masim, WH Hsu,
CH Tsai, HL Liu, M Porta, MT Nguyen, T Yonezawa, A Balcytis,
X Wang, S Juodkazis, and K Hatanaka, ¡§MHz-ultrasound generation by chirped
femtosecond laser pulses from gold nano-colloidal dispersions,¡¨ Optics Express, Vol. 24, No. 15,
pp. 24050-24059, 2016 (IF = 3.356, 19/96 in ¡§Optics¡¨) link
26.
FCP Masim, HL
Liu, M Porta, T Yonezawa, A Balcytis, S Juodkazis, WH Hsu, and K
Hatanaka, ¡§Enhanced photoacoustics from gold nano-colloidal suspensions
under femtosecond laser excitation,¡¨ Optics
Express, Vol. 24, No. 13, pp.14781-14792, 2016 (IF = 3.356,
19/96 in ¡§Optics¡¨) link
27.
J Xia, PH Tsui, HL
Liu*, ¡§Low-Pressure Burst-Mode Focused Ultrasound Wave
Reconstruction and Mapping for Blood-Brain Barrier Opening: A Preclinical
Examination,¡¨ Scientific Reports,
6:27939, doi:10.1038/srep27939., 2016 (*³q°T§@ªÌ; IF=4.122, 16/64 in ¡§
Multidisciplinary Sciences¡¨). link
28.
YW Chen, TY Liu, PH
Chang, PH Hsu, HL Liu, HC Lin, SY Chen, ¡§A theranostic
nrGO@MSN-ION nanocarrier developed to enhance the combination effect of
sonodynamic therapy and ultrasound hyperthermia for treating tumor,¡¨ Nanoscale, Vol. 8, No. 25,
pp.12648-57, 2016. (IF = 7.233, 25/165 in ¡§Chemistry, Multiplidiciplinary¡¨)
29.
CY Lin, HY Hsieh, CM Chen, SR Wu, CH Tsai, CY Huang, MY
Hua, KC Wei, CK Yeh, and HL Liu*,
"Non-invasive, Neuron-Specific Gene Therapy by Focused
Ultrasound-Induced Blood-Brain Barrier Opening in Parkinson¡¦s Disease Mouse
Model", Journal of Controlled Release, Vol. 235, pp. 72-81, 2016 (*³q°T§@ªÌ; IF =
7.877, 9/256 in ¡§Pharmacology & Pharmacy¡¨) link
30.
SS Li, CW Lin, KC Wei,
CY Huang, PH Hsu, HL Liu, YJ Lu, SC Lin, HW Yang*, CCM Ma*,
¡§Non-invasive screening for early Alzheimer's disease diagnosis by a
sensitively immunomagnetic biosensor¡¨, Scientific Reports, 6:25155. doi:10.1038/srep25155., 2016 (IF=5.228,
7/63 in ¡§ Multidisciplinary Sciences¡¨). link
31.
CH Fan, YH Cheng, CY
Ting, YJ Ho, PH Hsu, HL Liu*, CK Yeh*, ¡§Ultrasound/Magnetic
Targeting with SPIO-DOX-Microbubble Complex for Image-Guided Drug Delivery in
Brain Tumors,¡¨ Theranostics, Vol. 6, No. 10,
pp.1542-1556, 2016 (*³q°T§@ªÌ; IF =
8.537, 8/128 in ¡§Medicine, Research and Experimental¡¨). link
32.
MT Tsai, IC Lee, ZF
Lee, HL Liu, YC Choia, CC Wang, JD Lee1*, ¡§In vivo evaluation
of temporal effects and drug delivery induced by transdermal microneedles
with optical coherence imaging,¡¨ Biomedical
Optics Express, Vol. 7, No. 5, pp. 1865-1876, 2016 (IF = 3.482,
15/96 in ¡§Optics¡¨). link
33.
HL Liu, PH Hsu, CY Lin, CW Huang, WY Chai, PC Chu, CY
Huang, PY Chen, LY Yang, JS Kuo, KC Wei*, ¡§Focused Ultrasound Enhances CNS
Delivery of Bevacizumab for Malignant Glioma Treatment,¡¨ Radiology,
Vol. 281, pp. 99-108, 2016 (IF=7.469,
4/126 in¡§Radiology¡¨). link
34. CH Tsai, JW Zhang, YY Liao, HL Liu*, ¡§Real-time
monitoring of focused ultrasound blood-brain barrier opening via
subharmonic acoustic emission detection: Implementation of confocal
dual-frequency piezoelectric transducers,¡¨ Physics in Medicine and
Biology, Vol. 61, pp. 2926-2946, 2016 (*³q°T§@ªÌ; IF
= 2.665, 27/77 in ¡§Engineering, Biomedical¡¨) link
35. CH Fan, CY Ting, CY Lin, HL Chan, YC
Chang, YY Chen, HL Liu*,
and CK Yeh*, ¡§Noninvasive, Targeted, and Non-Viral Ultrasound-Mediated
GDNF-Plasmid Delivery for Treatment of Parkinson's Disease,¡¨ Scientific
Reports, 6:19579.
doi:10.1038/srep19579, 2016 (*³q°T§@ªÌ; IF=4.122, 16/64 in ¡§ Multidisciplinary
Sciences¡¨). link
36.
PC Chu**, HL Liu**, HY Lai, CY Lin, HC Tsai, YC Pei,
"Neuromodulation accompanying focused ultrasound-induced blood-brain
barrier opening," Scientific Reports, Vol. 5:
15477, 2015 (**Equal Contribution; IF=5.228, 7/63 in ¡§ Multidisciplinary
Sciences¡¨). link
37.
PY Chen, KC Wei, HL Liu*, ¡§Neural Immune
Modulation and Immunotherapy Assisted by Focused Ultrasound Induced
Blood-Brain Barrier Opening", Human Vaccines & Immunotherapeutics,
Vol. 11, no. 10, accepted, 2014 (*³q°T§@ªÌ; IF =
2.157, 79/161 in ¡§Biotechnology & Applied Microbiology¡¨). link
38.
CY Lin, HY Hsieh, WG Pitt, CY
Huang, IC Tseng, CK Yeh, KC Wei, HL
Liu*, ¡§Focused Ultrasound-Induced Blood-Brain Barrier Opening
for Non-Viral, Non-invasive, and Targeted Gene Delivery,¡¨ Journal of Controlled Release,
Vol. 212, pp.1-9, 2015 (*³q°T§@ªÌ; IF =
7.877, 9/256 in ¡§Pharmacology & Pharmacy¡¨)
link (Selected as ¡§Cover story¡¨ of the issue)
1.
AH Liao, HY Chou, YL Hsieh, SC
Hsu, KC Wei, and HL Liu*,
¡§Enhanced Therapeutic Epidermal growth factor receptor (EGFR) Antibody
Delivery via Pulsed Ultrasound with Targeting Microbubbles for Glioma
Treatment,¡¨ Journal of Medical and Biological Engineering, Vol. 1, pp.
1-9, Eng.
DOI 10.1007/s40846-015-0032-9, 2014 (SCI IF = 1.211,
55/76 in ¡§Engineering,
Biomedical¡¨). link (Selected as ¡§The paper of the year in JMBE¡¨)
2.
PY Chen, HY Hsieh, CY Huang, CY
Lin, KC Wei, and HL Liu*,
¡§Focused Ultrasound-Induced Blood-Brain Barrier Opening to Enhance
Interleukin-12 Delivery for Brain Tumor Immunotherapy: A Preclinical
Feasibility Study,¡¨ Journal of Translational Medicine, Vol. 13, No. 93, pp.
1-12, 2015 (*Corresponding
author; IF = 4.197, 28/128 in ¡§Medicine,
Res. & Exp¡¨). link
3.
CH Fan, CY Ting, YC Chang, KC
Wei, HL Liu*, and CK
Yeh*, "Drug-loaded Bubbles with Matched Focused Ultrasound Excitation
for Concurrent Blood-Brain Barrier Opening and Brain-Tumor Drug
Delivery," Acta Biomaterialia, Vol. 15, pp. 89¡V101, 2015 (*Corresponding
author; IF = 6.383, 3/78 in ¡§Engineering, Biomedical¡¨) link
4.
HY Huang**, HL Liu**, PH Hsu, CS Chiang, CH Tsai, HS Chi, SY Chen,
and YY Chen*, ¡§Multitheragnostic Nanobubble System to Induce Brain-Blood
Barrier Disruption with Magnetically Guided Focused Ultrasound,¡¨ Advanced
Materials, Vol. 27, pp. 655-661, 2015 (**Equal Contribution;
IF=21.95, 5/165 in ¡§Chemistry, Multidisciplinary¡¨) link
5.
HL Liu*, CY Huang,
JY Chen, HYJ Wang, PY Chen, and KC Wei, ¡§Pharmacodynamic and Therapeutic
Investigation of Focused Ultrasound-induced Blood-Brain Barrier Opening for
Enhanced Temozolomide Delivery in Glioma Treatment,¡¨ PLoS ONE, Vol. 9,
No. 12, e114311, 2014 (SCI
IF = 2.766, 15/64 in ¡§Multidisciplinary Sciences¡¨) link
(Highlight by Neurosurgery)
6.
KJ Chen, EY Chaung, SP Wey, KJ Lin, F Cheng,
CC Lin, HL Liu, HW Tseng,
CP L, MC W, CM Liu, and HW Sung, "Hyperthermia-Mediated Local Drug
Delivery by a Bubble-Generating Liposomal System for Tumor-Specific
Chemotherapy,¡¨ ACS Nano, Vol. 8, No. 5, pp. 5105-5115, 2014 (IF=13.7, 10/163 in ¡§Chemistry,
Multidisciplinary¡¨). link
7.
MT Tsai, FY Chang, CK Lee, CS Gong, YX Lin, JD
Lee, CH Yang, HL Liu*,
¡§Investigation of temporal vascular effects induced by focused ultrasound
treatment with speckle-variance optical coherence tomography,¡¨ Biomedical
Optics Express. Vol. 5, No. 7, pp. 2009-22, 2014. (*Corresponding
author; IF = 3.482, 15/96 in ¡§Optics¡¨). link
8.
CH Fan, WH Lin, CY Ting, WY Chai, TC Yen, HL Liu* and CK Yeh*,
¡§Contrast-Enhanced Ultrasound Imaging for the Detection of Focused
Ultrasound-Induced Blood-Brain Barrier Opening,¡¨ Theranostics, Vol. 4,
No. 10, pp. 1014-1025, 2014 (*Corresponding author; IF = 8.537, 8/128 in
¡§Medicine, Research and Experimental¡¨). link
9.
WY Chai, PC Chu, MY Tsai, YC Lin, JJ Wang, KC
Wei, YY Wai and HL Liu*,
¡§Magnetic-Resonance Imaging for Kinetic Analysis of Permeability Changes
during Focused Ultrasound-Induced Blood-Brain Barrier Opening and Brain
Drug Delivery,¡¨ Journal of Controlled Release, Vol. 192, pp.1-9, 2014 (SCI
IF = 7.877, 9/256 in ¡§Pharmacology & Pharmacy¡¨) link
10. J Xia, Q
Li,PY Chen, Z Zhou,CY Wang, HL
Liu, J Teng, and PH Tsui, "Considering Angle Selection When
Using Ultrasound Electrode Displacement Elastography to Evaluate
Radiofrequency Ablation of Tissues," BioMed Research International,
Volume 2014, ID 764320, 2014 (IF = 2.476, 81/161 in "Biotech. and App.
Microbiology")
11. CH Fan**, HL Liu**, CY Ting, YH Lee,
CY Huang, YJ Ma, KC Wei, TC Yen and CK Yeh, ¡§Submicron-Bubble-Enhanced
Focused Ultrasound for Blood¡VBrain Barrier Disruption and Improved CNS Drug
Delivery,¡¨ PLoS
ONE, Vol.9, No. 5,
e96327, 2014 (**Equal contribution, SCI IF = 2.766, 15/64 in
¡§Multidisciplinary Sciences¡¨) link
12.
X Geng, Z
Zhou, Q Li, S Wu, CY Wang, HL Liu,
CC Chuang, and PH Tsui, ¡§Comparison of ultraosund temperature imaging with
infrared thermometry during radio frequency ablation,¡¨ Japanese Journal of Applied
Physics, Vol. 53, No. 4, pp. 047001, 2014 (IF = 1.122, 97/145 in
Phycis, Applied)
13.
HL Liu*, CK Jan, PC Chu, JC Hong, PY Lee, JD Hsu, CC Lin, CY Huang, PY Chen,
and KC Wei*, ¡§Design and Experimental Evaluation of a 256-Channel
Dual-Frequency Ultrasound Phased-Array System for Transcranial Blood-Brain
Barrier Opening and Brain Drug Delivery,¡¨ IEEE Transactions on
Biomedical Engineering, Vol. 61, No. 4, pp.1350-1360, 2014 (IF=4.288, 9/78 in
¡§Engineering, Biomedical¡¨). link
14.
HL Liu, CH Fan, CY Ting, and CK Yeh, "Combining Microbubbles and Ultrasound
for Drug Delivery to Brain Tumors" Theranostics, Vol. 4,
No. 4, pp.432-444, 2014 (IF = 8.537, 8/128 in ¡§Medicine, Research and
Experimental¡¨). link
15. HW Yang, CY
Huang, CW Lin, HL Liu, CW
Huang, SS Liao, PY Chen, PW Hsu, YJ Lu, KC Wei, CCM Ma,
¡§Gadolinium-functionalized nanographene oxide as a nanocarrier for combined
drug and microRNA delivery and magnetic resonance imaging,¡¨ Biomaterials,
Vol., 35, No. 6534-42, 2014 (IF = 8.806, 1/78 in ¡§Engineering,
Biomedical¡¨). link
16.
JJ Xia, Q Li, HL Liu, WS Chen and PH Tsui,
"An Approach for the Visualization of Temperature Distribution in
Tissues According to Changes in Ultrasonic Backscattered Energy," Computational
and Mathematical Methods in Medicine, Volume 2013, Article ID
682827 (IF = 0.766).
17.
YW Huang, SH Hu, SY Hung, CS
Chiang, HL Liu, TL Chiou,
HY Lai, YY Chen, "SPIO Nanoparticle-Stabilized Nanobubbles with MR/US
Dual-Modality Imaging and HIFU-triggered Release Drug for in-vivo
Therapy," Journal of Controlled Release, Vol. 172, pp.118-127, 2013 (IF = 7.786, 10/256 in "Chemistry,
Multidisciplinary). link
18.
HW Yang, YJ Lu, KJ Lin, SC Hsu,
CY Huang, SH She, HL Liu,
MC Xiao, SP Wey, PY Chen, TC Yen, KC Wei, CCM Ma, "EGRF conjugated
PEGylated nanographene oxide for targeted chemotherapy and photothermal
therapy, " Biomaterials, Vol. 34, No. 29, pp. 7204-7214, 2013 IF =
8.806, 1/78 in ¡§Engineering, Biomedical¡¨).
link
19.
MT Tsai, CK Lee, KM Lin, YX Lin,
TH Lin, TC Chang and HL Liu*,
"Quantitative Observation Evaluation of Focused Ultrasound Induced
Vascular Leakage and Deformation after Focused Ultrasound Treatment
Exposure via by using Fluorescein Angiography and Optical Coherence
Tomography," Journal of
Biomedical Optics, Vol.18,
No. 10, pp.101307, 2013 (IF=2.53, 30/92 in ¡§Optics¡¨). link
20.
CY Wang, TS Yeh, XN Geng, HL Liu, and PH Tsui, "Monitoring Radiofrequency
Ablation with Ultrasound Nakagami Imaging," Medical Physics,
Vol.40, No.7, pp.072901, 2013. (IF=2.884, 36/126 in ¡§Radiology¡¨).
21.
H.W. Yang, M.Y. Hua, T.L. Hwang,
K.J. Lin, C.Y. Huang, R.Y. Tsai, C.C.M. Ma, P.H. Hsu, S.P. Wey, P.W. Hsu,
P.Y. Chen, Y.C. Huang, Y.J. Lu, T.C. Yen, L.Y. Feng, C.W. Lin, H.L. Liu*, K.C. Wei*. ¡§Noninvasive
synergistic treatment of brain tumor by targeted chemotherapeutic delivery
and amplified focused ultrasound-hyperthermia using magnetic nanographene
oxide,¡¨ Advanced Materials, Vol. 25, No. 26, pp.3605-3611,
2013. (*Corresponding author; IF=21.95, 5/165 in ¡§Chemistry,
Multidisciplinary¡¨). link
22.
HW Yang, HL Liu**, ML Li, IW Hsi, CT Fan, CY Huang, YJ Lu, MY
Hua, HY Chou, JW Liaw, CCM Ma and KC Wei, "Magnetic gold-nanorod/
PNIPAAmMA nanoparticles for dual magnetic resonance and photoacoustic
imaging and targeted photothermal therapy," Biomaterials, Vol.
34, pp.5651-5660, 2013. (**¦@¦P²Ä¤@§@ªÌ; IF =
8.806, 1/78 in ¡§Engineering, Biomedical¡¨). link
23.
PC Chu, WY Chai, HY Hsieh, JJ
Wang, SP Wey, CY Huang, KC Wei and
HL Liu*, "Pharmacodynamic Analysis of Magnetic Resonance
Imaging-Monitored Focused Ultrasound-Induced Blood-Brain Barrier Opening
for Drug Delivery to Brain Tumors," BioMed Research International,
Vol. 2013, pp. 627496, 2013 (*³q°T§@ªÌ; IF =
2.476, 81/161 in "Biotech. and App. Microbiology").link
24.
KC Wei, PC Chu, HYJ Wang, CY
Huang, PY Chen, HC Tsai, YJ Lu, IC Tseng, PY Lee, TC Yen, and HL Liu*, "Focused
Ultrasound-induced Blood¡VBrain Barrier Opening to Enhance Temozolomide
Delivery for Glioblastoma Treatment: A Preclinical Study, " PLoS ONE, Vol. 8, No. 3, pp. e58995,
2013 (*³q°T§@ªÌ; SCI IF = 2.766, 15/64
in ¡§Multidisciplinary Sciences¡¨) link
25.
C-H Fan, C-Y Ting, H-J Lin, C-H
Wang, H-L Liu*, T-C Yen,
C-K Yeh*, "SPIO-Conjugated, Doxorubicin-Loaded Microbubbles for
Concurrent MRI and Focused-Ultrasound Enhanced Brain-Tumor Drug
Delivery," Biomaterials, Vol. 34, pp. 3706-3715, 2013 (*¦@¦P³q°T§@ªÌ; IF
= 8.806, 1/78 in ¡§Engineering, Biomedical¡¨) link
26.
P-H Hsu, K-C Wei, C-Y Huang, C-J Wen, T-C Yen, C-L Liu, Y-T
Lin, J-C Chen, C-R Shen, and H-L
Liu*, "Noninvasive and targeted gene delivery into the brain
using microbubble-facilitated focused ultrasound, " PLoS
ONE, Vol. 8, No. 2, pp. e57682, 2013 (*³q°T§@ªÌ; SCI IF = 3.234, 8/56 in
" Multidisciplinary Sciences ") link
27.
K.J. Chen, H.F. Liang, H.L. Chen, Y.C. Wang, P.Y. Cheng, H.L. Liu, Y.N. Xia, H.W.
Sung, "A Thermoresponsive Bubble-Generating Liposomal System for
Triggering Localized Extracellular Drug Delivery", ACS
Nano, Vol. 7, No. 1, pp. 438-446, 2013 (IF=13.334, 8/163 in
¡§Chemistry, Multidisciplinary¡¨). link
28.
C-H Fan, C-Y Ting, H-L
Liu*, C-Y Huang, H-Y Hsieh, T-C Yen, K-C Wei, C-K Yeh,
"Antiangiogenic-targeting drug-loaded microbubbles combined with focused
ultrasound for glioma treatment, " Biomaterials, Vol.
34, pp. 2142-2155, 2013 (*¦@¦P³q°T§@ªÌ; IF = 8.806, 1/78 in
¡§Engineering, Biomedical¡¨). link
29.
K-C
Wei, H-C Tsai, Y-J Lu, H-W Yang, M-Y Hua, M-F Wu, P-Y Chen, C-Y Huang, T-C
Yen, and H-L Liu*, ¡§Neuronavigation-Guided Focused
Ultrasound-Induced Blood-Brain Barrier Opening: A Preliminary Study in
Swine,¡¨ American Journal of
Neuroradiology, Vol. 34, No. 1, pp. 115-120, 2013. (IF=3.55, 24/124 in ¡§Radiology¡¨) link
30. H-L Liu,
H-Y Hsieh, L-A Lu, C-W Kang, M-F Wu and C-Y Lin, "Low-Pressure Pulsed
Focused Ultrasound with Microbubbles Promotes an Anticancer Immunological Response,"
Journal
of Translational Medicine, Vol. 10: 221, 2012 (IF = 3.786, 30/128 in "Medicine, Res. & Exp") link
31. H-W Yang, M-Y Hua, K-J Lin, S-P Wey, R-Y
Tsai, S-Y Wu, Y-C Lu, H-L Liu,
Tony Wu, Y-H Ma, ¡§Bioconjugation of recombinant tissue plasminogen
activator to magnetic nanocarriers for targeted thrombolysis,¡¨ International
Journal of Nanomedicine, Vol. 7, pp. 1¡V11, 2012 (IF = 4.3, 26/83 in "Nanoscience &
Nanotechnology").
32. H-W Yang, M-Y Hua, H-L Liu, C-Y Huang, K-C Wei, ¡§Potential of magnetic nanoparticles for targeted drug delivery.¡¨ Nanotechnology, Science
and Applications, Vol.
5, pp. 73-86, 2012 (SCI).
33. A-H Liao, Y-K Li, W-J Lee, M-F Wu, H-L Liu, and M-L Kuo,
¡§Estimating the Delivery Efficiency of Drug-Loaded Microbubbles in Cancer
Cells with Ultrasound and Bioluminescence Imaging,¡¨ Ultrasound in Medicine and Biology, Vol. 38, No. 11, pp. 1938¡V1948, 2012 (IF=2.645, 7/32 in ¡§Acoustics¡¨).
34. P-H Liao, H-H Yang, P-T Chou, M-H Wang,
P-C Ju, H-L Liu, and L-K
Chen, "Sufficient virus-neutralizing antibody in the central nerve
system improves the survival of rabid rats," Journal of Biomedical
Sciences, Vol. 19: 61, 2012 (IF = 1.98)
35. Y-H Ma, S-Y Chen, S-J Tu, H-W Yang, H-L Liu, ¡§Manipulation of
magnetic nanoparticle retention and hemodynamic consequences in
microcirculation: assessment by laser speckle imaging,¡¨ International Journal of
Nanomedicine, Vol. 7, pp. 1¡V11, 2012 (IF = 4.3, 26/83 in "Nanoscience & Nanotechnology")
36. C-J Ke, Y-J Lin, Y-C Hua, W-L Chiang, K-J Chen, W-C Yang, H-L
Liu, C-C Fu, H-W Sung, ¡§Multidrug release based on microneedle
arrays filled with pH-responsive PLGA hollow microspheres,¡¨ Biomaterials, Vol. 33, No. 20, pp. 5156-5165, 2012.
(IF = 8.806, 1/78 in ¡§Engineering,
Biomedical¡¨).
37.
A-H Liao, H-L
Liu**, C-H Su, M-Y Hua, H-W Yang, Y-T Weng, P-H Hsu, S-M Huang, S-Y
Wu, H-El Wang, T-C Yen and P-C Li, ¡§Paramagnetic Perfluorocarbon-Filled
Albumin-(Gd-DTPA) Microbubbles for the Induction of Focused-Ultrasound-Induced
Blood¡VBrain Barrier Opening and Concurrent MR and Ultrasound Imaging,¡¨ Physics in Medicine and Biology,
Vol. 57, pp.2787-2802,
2012 (**¦@¦P²Ä¤@§@ªÌ; IF = 2.665, 27/77 in
¡§Engineering, Biomedical¡¨) link
38.
P-H Tsui, Y-C Shu,
W-S Chen, H-L Liu, I-T Hsiao, and Y-T Chien, "Ultrasound
temperature estimation based on probability variation of backscatter
data", Medical Physics,
Vol. 39, No. 5, pp. 2369-2385, 2012 (IF=2.884,
36/126 in ¡§Radiology¡¨).
39.
P-H Wang**, H-L
Liu**, P-H Hsu, C-R C Wang, P-Y Chen, K-C Wei, T-C Yen, and M-L Li,
"Gold-nanorod contrast-enhanced photoacoustic micro-imaging of
focused- ultrasound induced blood-brain barrier opening in a rat
model", Journal of Biomedical
Optics, Vol. 17, No. 6, pp. 061222, 2012 (**¦@¦P²Ä¤@§@ªÌ; IF= 2.556, 21/90 in ¡§Optics¡¨). link
40.
C-H
Fan, H-L Liu, C-Y Huang,
Y-J Ma, T-C Yen, C-K Yeh, ¡§Detection of intracerebral hemorrhage and
transient blood-supply shortage in focused ultrasound-induced
blood-brain-barrier disruption by ultrasound imaging,¡¨ Ultrasound in Medicine and Biology, Vol. 38, No. 8, pp. 1372¡V1382, 2012 (IF=2.645, 7/32 in ¡§Acoustics¡¨). link
41. P-H Tsui, Y-T Chien, H-L Liu, Y-C Shu, W-S Chen,
¡§Using ultrasound CBE imaging without echo shift compensation for
temperature estimation,¡¨ Ultrasonics, Vol. 52, No. 7, pp.
925-935, 2012. (IF=1.954, 8/32 in ¡§Acoustics¡¨)
42. H-W Yang**, M-Y Hua**, H-L Liu**, R-Y Tsai, S-T
Pang, P-H Hsu, H-J Tang, T-C Yen, C-K Chuang, ¡§An epirubicin-conjugated
nanocarrier with MRI function to overcome lethal multidrug-resistant
bladder cancer,¡¨ Biomaterials, Vol. 33, pp.
3919-3930, 2012. (**¦@¦P²Ä¤@§@ªÌ; IF = 8.806, 1/78 in ¡§Engineering, Biomedical¡¨). link
43. H-W Yang**, M-Y Hua**, H-L Liu**, R-Y Tsai, C-K
Chuang, P-C Chu,P-Y Wu, Y-H Chang, H-C Chuang, K-J Yu, and S-T Pang,
¡§Cooperative dual-activity targeted nanomedicine for specific and effective
prostate cancer therapy¡¨, ACS Nano, Vol.6, No. 2,
pp1795-1805, 2012 (**¦@¦P²Ä¤@§@ªÌ; IF=13.334, 8/163
in ¡§Chemistry, Multidisciplinary¡¨¡¨). link
44. Y-C Lin, T-H Chan, C-Y Chi, S-H Ng, H-L Liu, K-C Wei, Y-Y Wei,
C-C Wang, J-J Wang, ¡§Blind Estimation of Arterial Input Function in Dynamic
Contrast-Enhanced MRI using Purity Maximization,¡¨ Magnetic Resonance in
Medicine, Vol. 68, No. 5, pp.
1439-1449, 2012 (IF=4.082,
19/126 in ¡§Radiology¡¨)
45.
H-L Liu, H-W Yang, M-Y Hua, and K-C Wei, ¡§Enhanced Therapeutic Agent
Delivery via MRI-Monitored Focused Ultrasound Blood-Brain Barrier
Disruption for Brain Tumor Treatment: An Overview of the current
Preclinical Status,¡¨ Neurosurgical
Focus, Vol. 32,
No. 1, E4, 2012 (IF
= 3.139, 39/196 in ¡§Surgery¡¨). link
46.
C-Y Ting, C-H Fan, H-L
Liu*, C-Y Huang, H-Y Hsieh, T-C Yen, K-C Wei, C-K Yeh*, ¡§Concurrent
blood-brain barrier opening and local drug delivery using drug-carrying
microbubbles and focused ultrasound for brain glioma treatment,¡¨ Biomaterials, Vol. 33, pp.
704-712, 2012 (*Co-corresponding author, IF = 8.806, 1/78 in
¡§Engineering, Biomedical¡¨). link
47.
M-T Tsai, T-D Chi, H-L Liu, F-Y Chang, C-H
Yang, C-K Lee, and C-C Yang, ¡§Microvascular imaging using swept-source
optical coherence tomography with single-channel acquisition,¡¨ Appl.
Phys. Express, Vol. 4,
pp.097001-3, 2011 (IF =2.365, 21/125 in ¡§Physics, Applied¡¨).
48.
W-S
Chen, H-L Liu, Y.S. Tung, J.C. Wang, Y.H. Ding, C.K. Jan,
¡§Reducing lesion aberration by dual-frequency focused ultrasound
ablations,¡¨ International Journal
of Hyperthermia, Vol. 27, No. 7, pp. 637-647, 2011 (IF=2.645, 37/125in ¡§Radiology¡¨).
49.
C-J Ke, T-Y Su, H-Chen, H-L
Liu, W-L Chiang, P-C Chu, Y Xia, H-W Sung, ¡§Smart Multifunctional
Hollow Microspheres for the Quick Release of Drugs in Intracellular
Lysosomal Compartments,¡¨ Angewandte Chemie International Edition,
Vol. 50, No. 35, pp. 8086 ¡V 8089, 2011 (IF
= 11.994, 13/157 in ¡§Chemistry, Multidisciplinary¡¨)
50.
M-Y Hua**, H-W Yang**, H-L
Liu**, R-Y Tsai, S-T Pang, K-L Chuang, Y-S Chang, T-L
Hwang, Y-H Chang, H-C Chuang, C-K Chuang, ¡§Superhigh-magnetization
nanocarrier as a doxorubicin delivery platform for magnetic targeting
therapy,¡¨ Biomaterials, Vol. 32, pp. 8999-9910, 2011 (**¦@¦P²Ä¤@§@ªÌ, IF =
8.806, 1/78 in ¡§Engineering, Biomedical¡¨). link
51.
J-J
Wang , W-Y Lin, C-S Lu, Y-H Weng, S-H Ng , C-H Wang , H-L Liu,
R-H Hsieh , Y-L Wan, and Y-Y Wai, ¡§Parkinson Disease_Diagnostic Utility of
Diffusion Kurtosis Imaging,¡¨ Radiology,
Vol. 261, No. 1, pp. 210-217 (IF=7.469, 4/126
in¡§Radiology¡¨).
52.
H-L Liu, P-Y Chen, H-W Yang, J-S
Wu, I-C Tseng, Y-J Ma, C-Y Huang, H-C Tsai, S-M Chen, Y-J Lu, C-Y Huang, M-Y Hua,
Y-H Ma, T-C Yen and K-C Wei, ¡§In Vivo MR Quantification of
Superparamagnetic Iron Oxide Nanoparticle Leakage During
Low-frequency-ultrasound¡Vinduced Blood¡VBrain Barrier Opening In Swine,¡¨ Journal of Magnetic Resonance
Imaging, Vol. 34, No. 12, pp.
1313-1324, 2011 (IF=3.083, 23/125 in
¡§Radiology¡¨). link
53.
H-W
Yang**, M-Y Hua**, H-L Liu**, C-Y Huang, R-Y Tsai, Y-J Lu,
J-Y Chen, H-J Tang, H-Y Hsien, Y-S Chang, T-C Yen, P-Y Chen and K-C Wei,
¡§Self-protecting core-shell magnetic nanoparticles for targeted, traceable,
long half-life delivery of BCNU to gliomas,¡¨ Biomaterials, Vol. 32, pp. 6523-6532, 2011 (**¦@¦P²Ä¤@§@ªÌ, IF = 8.806,
1/78 in ¡§Engineering, Biomedical¡¨).
link
54.
W-S
Chen, C-C Shen, C-T Ko, C-H Cheng, H-L Liu, M-C Ho, C-N Chen,
C-K Yeh, ¡§Single-Element Ultrasound Transducer for Combined Vessel
Localization and Ablation,¡¨ IEEE Trans. Ultrason. Ferroelectrics Freq. Contr., Vol. 58, No. 4, pp.
766-775, 2011 (IF = 1.512, 10/31 in ¡§Acoustics¡¨)
55.
H-L Liu, M-L Li, P-H Tsui, M-S Lin, S-M Huang, and J
Bai, ¡§An Unified Approach to Combine Temperature Estimation and
Elastography for Thermal Lesion Determination in Focused Ultrasound Thermal
Therapy,¡¨ Physics in Medicine and
Biology, Vol. 56, pp. 169-186, 2011. (IF =
2.665, 27/77 in ¡§Engineering, Biomedical¡¨) link
56.
M-Y
Hua**, H-L Liu**, H-W Yang, P-Y Chen, R-Y Tsai, C-Y Huang,
I-C Tseng, L-A Lyu, C-C Ma, H-J Tang, T-C Yen, K-C Wei, ¡§The effectiveness
of a magnetic-nanoparticle-based delivery system for BCNU in the treatment
of gliomas,¡¨ Biomaterials,
Vol. 32, pp. 512-523, 2011 (**¦@¦P²Ä¤@§@ªÌ, IF = 8.806, 1/78 in
¡§Engineering, Biomedical¡¨). link
57.
H-L Liu, S-M Huang, and M-L Li, ¡§High frame rate ultrasound monitoring of
high intensity focused ultrasound induced temperature changes: a novel
asynchronous approach,¡¨ Medical
Physics, Vol. 37, No. 11, pp. 5921-5928, 2010 (IF=2.884, 36/126 in ¡§Radiology¡¨).
link
58.
H-L Liu, M-Y Hua, H-W Yang, C-Y Huang, P-C Chu, J-S Wua, I-C Tseng, J-J
Wang, T-C Yen, P-Y Chen, and K-C Wei, ¡§Magnetic resonance monitoring of
focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic
agents to the brain,¡¨ Proceedings
of National Academy of Science USA, Vol. 107, No. 34, pp.15205-15210, 2010 (IF=9.504, 5/74 in ¡§Multidisciplinary
sciences¡¨). link
59.
K-C Ju and H-L
Liu, ¡§Zero-crossing-tracking technique for noninvasively ultrasonic
temperature estimation,¡¨ Journal
of Ultrasound in Medicine, Vol. 29, pp.1607¡V1615, 2010 (IF=1.402, 13/31 in ¡§Acoustics¡¨).
60.
P-Y Chen**, H-L
Liu**, M-Y Hua, H-W Yang, C-Y Huang, P-C Chu, L-A Lyu, H-C Tsai,
S-M Chen, Y-J Lu, J-J Wang, T-C Yen, Y-H Ma, T. Wu, J-P Chen, J-I Chuang,
J-W Shin, C. Hsueh, and K-C Wei, ¡§Novel Magnetic/Ultrasound Focusing System
Enhances Nanoparticle Drug Delivery for Glioma Treatment,¡¨ Neuro-oncology, Vol. 12, No. 10,
pp.1050-1060, 2010 (**¦@¦P²Ä¤@§@ªÌ, IF=9.384, 15/194 in ¡§Clinical Neurology¡¨).
link
61.
H-L Liu, M-Y Hua, P-Y Chen, P-C Chu, C-H Pan, H-W Yang,
C-Y Huang, J-J Wang, T-C Yen
and K-C Wei, ¡§Blood¡VBrain Barrier Disruption by Focused Ultrasound Enhances
Delivery of Chemotherapeutic Drugs for Glioblastoma Treatment,¡¨ Radiology, Vol. 255, No. 2, pp. 415-425, 2010 (IF=7.469, 4/126 in¡§Radiology¡¨) link
62.
H-L Liu, C-L Hsu, S-M Huang and Y-W Hsi, ¡§Focal Beam Distortion and
Treatment Planning for Transrib Focused Ultrasound Thermal Therapy: A
Feasibility Study Using a Two-dimensional Ultrasound Phased Array,¡¨ Medical Physics, Vol. 37, No. 2, pp. 848-860, 2010 (IF=2.884, 36/126 in
¡§Radiology¡¨).link
63.
H-L Liu, C-H Pan, C-Y Ting and M-J Hsiao, ¡§Opening of the Blood-Brain
Barrier By Low-Frequency (28-kHz) Ultrasound: A Novel Pinhole-Assisted
Mechanical Scanning Device,¡¨ Ultrasound
in Medicine and Biology, Vol. 36, No. 2, pp. 325-335, 2010 (IF=2.645, 7/32 in ¡§Acoustics¡¨). link
64.
Y-C Lin, C-C Wang,
Y-Y Wai, Y-L Wan,S-H Ng, Y-L Chen, H-L Liu, J-J Wang,
¡§Significant temporal evolution of diffusion anisotropy for evaluating of
early response to radiosurgery in patients with vestibular schwannoma:
findings from functional diffusion maps,¡¨ American Journal of Neuroradiology, Vol. 31, pp. 269-274,
2010. (IF=3.55, 24/124 in ¡§Radiology¡¨)
65.
H-L Liu, Y-Y Wai, P-H Hsu, L-A Lyu, J-S Wu, C-R Shen, J-C Chen, T-C Yen, and
J-J Wang, ¡§In Vivo Assessment of Macrophage CNS Infiltration during
Disruption of the Blood¡Vbrain Barrier with Focused Ultrasound: A Magnetic
Resonance Imaging Study,¡¨ Journal
of Cerebral Blood Flow & Metabolism, Vol. 30, pp. 168-177, 2010 (IF=5.081, 33/252 in ¡§Neuroscience¡¨). link
66.
J-J Wang, Y-Y Wai, Y-H Weng, K-K Ng, Y-Z Huang; L. Ying, H-L Liu, and C-H Wang,
¡§Functional MRI in the assessment of cortical activation during
gait-related imaginary tasks,¡¨ Journal of Neural Transmission,
Vol. 116, pp. 1087 ¡V 1092, 2009 (IF=2.402,
125/243 in ¡§Neuroscience¡¨).
67.
H-L Liu, M-L Li, T-C Shih, S-M Huang, I-Y Lu, D-Y Lin, S-M
Lin and K-C Ju, "Instantaneous Frequency Based Ultrasonic Temperature
Estimation during Focused Ultrasound Thermal Therapy," Ultrasound in Medicine and Biology,
Vol. 35, No. 10, pp. 1647-1661, 2009
(IF=2.214, 5/29 in¡§Acoustics¡¨).
68.
K-J
Lin**, H-L Liu**, P-H Hsu, Y-H Chung,W-C Huang, J-C Chen, S-P
Wey, T-C Yen, I-T Hsiao, ¡§Quantitative microSPECT/CT for detecting focused
ultrasound induced blood-brain barrier opening in the rat,¡¨ Nuclear Medicine and Biology,
Vol. 36, No. 7, pp. 853-867, 2009 (**¦@¦P²Ä¤@§@ªÌ, IF=2.412,
42/125 in ¡§Radiology¡¨).
69.
H-L Liu and C-M Hsieh, "Single-Transducer
Dual-Frequency Ultrasound Generation to Enhance Acoustic Cavitation," Ultrasononics Sonochemistry,
Vol. 16, No. 3, pp. 431-438, 2009 (IF=6.012,
1/31 in ¡§Acoustics¡¨).
70.
H-L Liu, P-H Hsu, P-J Ju, Y-Y Wai, J-C Chen, C-R Shen,
T-C Yen, and J-J Wang, "Magnetic Resonance Imaging Enhanced by
Superparamagnetic Iron Oxide Particles: Usefulness for Distinguishing
Between Focused Ultrasound-Induced Blood-Brain Barrier Disruption and Brain
Hemorrhage," Journal of
Magnetic Resonance Imaging, Vol. 29, No. 1, pp. 31-38, 2009 (IF=3.210, 23/125 in ¡§Radiology¡¨).
71.
H-L Liu, H-W Chen, Z-H Kuo, and W-C Huang, ¡§Design and Experimental
Evaluations of a Low-Frequency Hemispherical Ultrasound Phased-Array System
for Transcranial Blood-Brain Barrier Disruption¡¨ IEEE Transactions on Biomedical Engineering, Vol.55, No. 10, pp. 2407-2416.,
2008 (IF=4.288, 9/78 in ¡§Engineering,
Biomedical¡¨).
72.
J-J Wang, Y-C Lin,
Y-Y Wai, H-L Liu, C-P Lin, Y-Z Huang, ¡§Visualization of the
coherence of the principal diffusion orientation: an eigenvector-based
approach,¡¨ Magnetic
Resonance in Medicine, Vol. 59, No. 4, pp.764-770, 2008 (IF=3.267, 22/120 in ¡§Radiology¡¨).
73.
H-L Liu, Y-Y Wai, W-S Chen, J-C Chen, P-H Hsu, X-Y W, W-C Huang, T-C Yen,
and J-J Wang, ¡§Hemorrhage Detection during Focused-Ultrasound Induced
Blood¡VBrain-Barrier Opening by Using Susceptibility-Weighted Magnetic
Resonance Imaging,¡¨ Ultrasound in
Medicine & Biology, Vol. 34, No. 4, pp. 598-606, 2008 (IF=2.645, 7/32 in ¡§Acoustics¡¨).
74.
T-C Shih, H-L
Liu, K-C Ju, C-S Huang, P-Y Chen, H-W Huang, Y-J Ho, ¡§The
feasibility of heating on tumor periphery by using high intensity focused
ultrasound thermal surgery,¡¨ Int.
Comm. Heat Mass Trans., Vol. 35, pp. 439-445, 2008 (IF=2.315, 8/54 in ¡§Thermodynamics¡¨).
75.
H-L Liu, H Chang, W-S Chen, T-C
Shih, J-K Hsiao, and W-L Lin, ¡§Feasibility of Transrib Focused Ultrasound
Thermal Ablation for Liver Tumors Using a Spherically Curved 2D Array: A
Numerical Study,¡¨ Medical Physics, Vol. 34, No. 9,
pp. 3436-3448, 2007 (IF=2.884, 36/126 in
¡§Radiology¡¨).
76.
H-L Liu , T-C
Shih , W-S Chen and K-C Ju,¡§A Novel Strategy to Increase Heating Efficiency
in a Split-Focus Ultrasound Phased Array,¡¨ Medical Physics, Vol. 34, No. 7, pp. 2957-2967, 2007 (IF=2.884, 36/126 in
¡§Radiology¡¨).
77.
H-L Liu, W-L Lin, and Y-Y Chen , ¡§A Fast and Conformal
Heating Scheme for Producing Large Thermal Lesions Using a 2-D Ultrasound
Phased Array,¡¨ International
Journal of Hyperthermia, Vol. 23, No. 1, pp. 69 ¡V 82, 2007 (IF=2.645, 37/125in ¡§Radiology¡¨).
78.
H-L Liu, Y-Y Chen, W-S Chen, T-C Shih, J-S Chen, and W-L Lin,
"Interactions between consecutive sonications for characterizing the
thermal mechanism in focused ultrasound therapy,¡¨ Ultrasound in Medicine & Biology, Vol. 32, No. 9, pp.
1411 ¡V 1421, 2006 (IF=2.645, 7/32 in
¡§Acoustics¡¨).
79.
Y-S Tung, H-L
Liu, C-C Wu, K-C Ju, W-S Chen, and W-L Lin, ¡§Contrast-agent
enhanced ultrasound thermal ablation,¡¨ Ultrasound in Medicine & Biology, Vol. 32, No. 7, pp.
1103 ¡V 1110, 2006 (IF=2.645, 7/32 in ¡§Acoustics¡¨).
80.
W-S Chen, C-C Wu,
S-Y Fang, H-L Liu* (Corresponding author),
¡§Differences in the lesion formation process between focused ultrasound and
microwave ablations,¡¨ Medical
Physics, Vol. 33, No. 5, pp. 1346-1351, 2006 (IF=2.884, 36/126 in ¡§Radiology¡¨).
81.
H-L Liu, W-S Chen, J-S Chen, T-C Shih, Y-Y Chen, and W-L Lin,
"Cavitation - Enhanced Ultrasound Thermal Therapy by Combined Low- and
High-Frequency Ultrasound Exposure,¡¨ Ultrasound
in Medicine & Biology, Vol. 32, No. 5, pp. 759-767, 2006 (SCI IF:2.021, 4/31 in¡§Acoustics¡¨).
82.
T-C Shih, H-L
Liu, and Allen T-L Horng, ¡§Cooling effect of thermally significant
blood vessels in perfused tumor tissue during thermal therapy,¡¨ Int. Comm. Heat Mass Trans.,
Vol. 33, pp. 135-141, 2006 (IF=2.315,
8/54 in ¡§Thermodynamics¡¨).
83.
W-S
Chen, P-M Ma, H-L Liu, C-K Yeh, M-S Chen, and C-W Chang,
"A novel method for estimating the focal size of two confocal
high-intensity focused ultrasound transducers," J. Acoust. Soc. Am., Vol. 117, No. 6, pp.3740-3749, 2005 (IF=1.646, 9/31 in ¡§Acoustics¡¨).
84.
H-L Liu, Nathan McDannold, and K. Hynynen, ¡§Focal beam
distortion and treatment planning in abdominal focused ultrasound surgery,¡¨
Medical Physics, Vol. 32,
pp.1270-1280, 2005 (IF=2.884, 36/126
in ¡§Radiology¡¨).
85.
H-L Liu, Y-Y Chen, J-Y Yen and W-L Lin, ¡§A Pilot Point Temperature
Regulation for Thermal Dose Control during Ultrasound Thermal Therapy,¡¨ Medical & Biological Engineering & Computing, Vol. 42, pp. 178-188, 2004 (IF=1.791,
33/79 in ¡§Engineering, Biomedical¡¨).
86.
H-L Liu, Y-Y Chen, J-Y Yen, W-L Lin, ¡§Thermal lesion formation and
determination in external ultrasound thermal therapy,¡¨ Biomedical
Engineering ¡V Applications,
Basis, and Communications, Vol. 15, No. 3, pp. 124-132, 2003 (EI ).
87.
H-L Liu, Y-Y Chen, J-Y Yen and W-L Lin, ¡§Treatment time reduction for large
thermal lesions by using a multiple 1-d ultrasound phased array system,¡¨ Physics
in Medicine and Biology, Vol. 48, pp.1173-1190, 2003 (IF=2.701, 19/79 in ¡§Engineering,
Biomedical¡¨).
88.
W-L Lin, T-C Liang,
J-Y Yen, H-L Liu and Y-Y Chen, ¡§Optimization of power deposition and a heating
strategy for ultrasound thermal therapy,¡¨ Medical Physics,
Vol. 28, No. 10, pp. 2172-2181, 2001 (IF=2.884,
36/126 in ¡§Radiology¡¨).
89.
Y-Y Chen, W-L Lin, H-L Liu, J-Y Yen and M-J Shieh, ¡§Self-tuning fuzzy logic control for
ultrasound hyperthermia with reference temperature based on objective
functions,¡¨ Medical Physics, Vol. 26, No. 5, pp. 825-833,
1999 (IF=2.884, 36/126 in ¡§Radiology¡¨).
(B) Patents
l H-L Liu,
S-F Chen, and H Chang, "Multiple-Frequency Ultrasonic Phased Array
Driving System, " EU Patent
No. EP2640465, Nov. 7, 2018.
l H-L Liu,
K-C Wei, H-C Tsai, L-Y Lu, " Neuronavigation-guided focused ultrasound
system and method thereof," EU Patent No. EP2858619A4, 2018.
l H-L Liu,
K-C Wei, H-C Tsai, L-Y Lu, " Neuronavigation-guided focused ultrasound
system and method thereof," CA Patent No. CN103479403B, 2016.
l HL Liu, KC Wei, PY
Chen, PH Hsu, PC Chu, WY Chai, CY Lin, Method for ultrasound mediated
delivery system to monitor molecular penetration, US Patent, 10076652B2,
Sept. 18, 2017.
l HL Liu, MT Tsai, CK Yeh,
Imaging devices, systems, and methods of operation for acoustic-enhanced
optical coherence tomography, US Patent 15702574, 2018.
l ¼B¯E¿C¡B½²§»ªN¡B¿c§¤¯¡BÃQ°ê¬Ã¡A¡§¥H¤â³N¾É¯è¨t²Î¾É¤Þ»EµJ¦¡¶WµªiÄÀ©ñ¯à¶q¤§¨t²Î¤Î¨ä¤èªk¡A¡¨¿D¬w, 2013271506, 2017.
l ¼B¯E¿C¡B½²©sÀé¡B¸¯´¥ú¡AÁnPÅã¼v¼W±j¥ú¦P½Õ¼v¹³¤§ÃèÀY¤Î¨ä¨t²Î©M¹B§@¤èªk¡A¤¤µØ¥Á°ê(µo©ú),I616690, 2018.
l ¼B¯E¿C¡B½²§»ªN¡B¿c§¤¯¡BÃQ°ê¬Ã¡A¡§¤â³Nナビゲーションシステムを¥Îいた¶°§ô¶Wµªi©ñ¥Xエネルギーの»¤¾Éシステムとその¤èªk¡A¡¨¤é¥» (µo©ú), ¯S³\²Ä6188036, July 22, 2017.
l HL Liu, CH Tsai, KC Wei, PY Chen,
¡§Processing system and processing method for confocally emitting and
receiving ultrasound,¡¨ U.S.
Patent, US9743908B2, 2017.
l HL Liu and MS Lin,
¡§High-intensity focused ultrasound thermal therapy ablation apparatus
having integrated temperature estimation and elastography for thermal
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l ¼B¯E¿C¡AªL«T¦w¡A¶Wµªi§Y®É¥\率ºÊ±±¨t²Î¡A¤¤µØ¥Á°ê(µo©ú), ±M§Q¸¹I489802, June 21,
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l µØ¨N©É¡B¼B¯E¿C¡B·¨¶£½«¡BÃQ°ê¬Ã¡B³¯«~¤¸¡B½²ºa·½¡A¨ã¦³¦h«¤ÏÀ³©Ê©x¯à°ò¤§ºÏ©Ê©`¦Ì²É¤l½Æ¦Xª«¤Î¨ä»s³Æ¤èªk¡A¤¤µØ¥Á°ê(µo©ú), I445550, 7/21¡A2014.
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l ¼B¯E¿C¡B³¯¤åµ¾¡B¸âµ{³Í,"¤@ºØ§Îª¬°O¾Ð¦Xª÷ªº±±¨î¾¹¸Ë¸m©M±±¨î¤èªk,¡¨ ¤¤µØ¥Á°ê(µo©ú), ±M§Q¸¹I367410, July 1, 2012.
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l ¼B¯E¿C¡B³¢Âí»¨¡B³¯«í¤å¡A¡§¥Íª«ÂåÀø¥Î¥b¶êÀY¸n¦¡¶Wµªi¬Û¦ì°}¦C¸Ë¸m,¡¨ ¤¤µØ¥Á°ê(µo©ú), ±M§Q¸¹I337087, Feb. 11,
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